Hepatic Nuclear Factor 1B Mutations


Hepatic Nuclear Factor 1B Mutations cause an autosomal dominant disease that causes renal cysts and diabetes (RCAD) syndrome.


Link to Reviews or Guidelines


 Further Information

  • Verhave, J.H. et al. (2016). Hepatocyte Nuclear Factor 1β–Associated Kidney Disease: More than Renal Cysts and Diabetes. JASN 27 (2); 345-353.
  • Clissold R.L. et al. (2015). HNF1B-associated renal and extra-renal disease–an expanding clinical spectrum. Nature Reviews Nephrology 11 (2); 102-112.


More detailed Information for Health Professionals will be available on the ARRK website in the near future.

If you would like to form or be part of a Disease Specific Research Group (DSRG) for Hepatic Nuclear Factor 1B Mutations, please contact the ARRK registry (arrkregistry1@gmail.com) or Dr Hugh McCarthy (hugh.mccarthy@health.nsw.gov.au).


The resources on this page provide information for healthcare professionals. If you have questions about a medical condition or health related issue, please consult your medical doctor or a healthcare professional.


This page was last updated on 24th Oct, 2018.